John Henry Tilden publica en 1921 su obra central Impaired Health: Its Cause And Cure Vol, donde expone los principios y fundamentos de la toxemia como origen de los problemas de salud que afligen a la humanidad. Tilden sistematiza un concepto nuclear de la epistemología, metodología, tecnología y praxiología de Naturopatía recogiendo la tradición egipcia, grecolatina y oriental donde también singularizan los problemas derivados del concepto de toxemia que Tilden desarrolla en su obra.

La obra está divide en los siguientes capítulos:

Man A Digestive Apparatus

Bacteria Necessary

The Sterilized Are Sick And Die

Fermentation And Decomposition Defined

Fermentation And Decomposition Defined. Continued

The Philosophy Of Toxin Poisoning

The Limitation Of Putrefactive Fermentation

Why Contagious And Infectious Diseases Have Declined

Chapter I. The Science And Art Of Medicine

The Science And Art Of Medicine. Continued

Chapter II. Disease – What Is It?

Chapter III. The Study Of Medicine

I. Pathology
Crises
Etiology

1. Enviromnent In Its Relationship To Health And Disease
Cell-Life

2. Physical Agents.
Air
Altitude
Altitude. Continued
Heat
Heat. Continued
Cold
Light
Sound
Sound. Continued
Electricity
Electricity. Continued

3. Chemical Agents. Caustics
Toxin (Poison)
Alimentary Poison
Beverages
Lead
Poisons In The Air

4. Animate Agents. History Of Infection
History Of Infection. Part 2
History Of Infection. Part 3
History Of Infection. Part 4
History Of Infection. Part 5
A Reasonable Explanation Of Germ Action
A Reasonable Explanation Of Germ Action. Continued

5. Nervous Reactions
Nervous Reactions. Part 2
Nervous Reactions. Part 3
Nervous Reactions. Part 4
Mental Or Physical Reactions
Influence Of Sex In Bringing About Shock In The Human Species

6. Nutrition
Necessary To Cell-Buildin
Functions Of Nutrition
Fasting
Liquefying Food
Liquefying Food. Part 2
Liquefying Food. Part 3
Chlorosis
Emotional Disturbances
Urea
Disturbed Nutrition
Auto-Intoxication
Toxins In The Tissues Of The Body In Standard Healt
The Toxicity Of Urine
Overworked Organs
Auto-Intoxication From Enervated Skin, Lungs, And Kidneys
Lactic Acid Poisoning

7. Diatheses
Diatheses. Part 2
Diatheses. Part 3Scrofulous–Adenitis–Or Tubercular Diathesis
Characteristics Of The Scrofulous Subject
Gouty Diathesis

8. Heredity
Heredity. Continued
Cause Of Crime
Degeneration Is Not Transmissible
Why Criminals Do Not Reform
The Possibilities Of A Child

9. Pathology Of The Fetus
Pathology Of The Fetus. Part 2
Pathology Of The Fetus. Part 3
Benevolent Assimilation–A Conservative Force
Influence Of Chronic Intoxications
Saturnism (Lead Poisoning)
Hereditary Syphilis
Hereditary Syphilis. Continued

10. Inflammation
Inflammation. Continued
The Wound And Natures Mechanism
Inflammations Of Mucous Membranes

11. Septicemia And Pyemia
Bacteriemia
Septicemia
Sclerosis
Reparation Of Lesions
Intoxications Of All Kinds
Where Sclerosis Gets Its Origin
Arteriosclerosis
Histology. Tissue
Teratology
Cancer
Histogenetic Tumors
Adenoma
When Does A Cancer Become A Cancer?
Cause Of Fibroid Tumor

13. Synergies
Synergies. Continued
Heart weakness
Embolism
Nerve Connections
Inflammation
Suppuration
Purulent Foci
Chyliform Collections
Gangrene
Tubercles
Localization And Evolution Of Tuberculosis

B. Pathogeny

C. Pathological Physiology

D. Pathological Anatomy

E. Symptomatology

The Patient. Part 2

The Patient. Part 3

2. Appearance Of Patient

– Facial Expressions

– Skin

– Cerebral Derangements

– A Normal Person–Hunger

– An Abnormal Person-Appetite

3. Pain

– Relationship Of Pain To Other Facts Connected With Disease

– Pain Explained

4. Examination Of The Patient

(A) Organs Of Special Sense

(B) Vasomotor

(C) Heart

– Percussion

– The Normal Heart Sounds

– Disturbed Heart Rhythm

(D) Respiratory Apparatus

(E) Digestive Apparatus

– Flatulency

– Vomiting

– Stomach

– Intestine

– Fecal Matter

– Abdominal Pain And What It Signifies

– Abdominal Pain And What It Signifies. Continued

– Obscurity Of Abdominal Symptoms

– Volvulus (Twist In The Bowels)

– Liver

(F) Urinary Apparatus

– Chyluria

(G) Genital Organs

– Genital Organs. Continued

– Leucorrhea

– Abortion Habit

(H) The Nervous System

– Gait

– Convulsions

-Trembling Or Tremor

(F) Nosology

II. Diagnosis

III. Prognosis

IV. Therapeutics

Nature’s Plan as Concerns Utilization of Building Material

Vitamin–What Is It?

Vitamin–What Is It? Part 2

Vitamin–What Is It? Part 3

Vitamin–What Is It? Part 4

Vitamin–What Is It? Part 5

Vitamin–What Is It? Part 6

Vitamin–What Is It? Part 7

Vitamin–What Is It? Part 8

Vitamin–What Is It? Part 9

Vitamin–What Is It? Part10

Vitamin–What Is It? Part11

Archaic Medicin

Con su teoría de la toxemia, John Tilden reconoció el papel del estrés en la causa de los problemas de salud mucho antes de que esto se convirtiera en una idea aceptada. Señaló que la salud se altera cuando la energía nerviosa se disipa y el cuerpo ya no es capaz de eliminar adecuadamente los subproductos tóxicos del metabolismo. El estado resultante de la auto-intoxicación, o toxemia, fue considerado por Tilden como causa básica única de deterioro de la salud. A su juicio, cada enfermedad es un esfuerzo de la naturaleza por eliminar la toxemia, o crisis de la toxemia. Según Tilden, la energía nerviosa podría convertirse en tóxica al consumir los alimentos equivocados, por comer en exceso, teniendo en cuenta también muchos estimulantes como el café y el alcohol, y también por otras fuentes de estrés, tales como tensiones emocionales y mentales. En 1910 comenzó a publicar una revista mensual llamada The Stuffed Club, que continuó hasta 1915 cuando cambió el nombre por el de Philosophy of Health, y que pasó a llamarse más tarde, en 1926, Health Review and Critique